Global Acne Vulgaris Market: Snapshot
Acne vulgaris-one of the commonest skin disorders-has a multifactorial pathogenesis and is found mainly among adolescents. The pathogenetic mechanism usually consists of four key factors: increased sebum productions, follicular epidermal hyperproliferation, the colonization of bacteria Propionibacterium acnes (P. acne), and effects of inflammation. Successful management of the disease requires a better understanding of various pathogenetic factors and identifying the etiology of the acne in patients. Recent researches in targeted therapeutic modalities have given rise to a host of treatments that meet the specific expectations of the patients and provide enhanced tolerability as well. New treatment options focus on a permutation and combination of anti-acne agents, which are available in the market in varied compositions and formulations.
A vast assortment of topical and systemic drugs available in the market is set to expand therapeutic options for a greater number of patients depending on the stage and symptoms of the disease. Some of the prominent therapies recommended for treating acne vulgaris are: use of topical retinoid, combination therapy, hormonal therapies, antibiotics, and oral isotretinoin.
Benzoyl peroxide and topical retinoids are the most widespread treatments preferred by dermatologists. Available in different formulations such as lotions, washes, gels, and creams, they can target a wide spectrum of bacterial agents in cases of mild-to-moderate acne vulgaris and have significant anti-inflammatory effects. The efficacy of retinoids have already been proven for over three decades. Dermatologists prefer this as the first-line of treatment for mild-to-moderate noninflammatory and inflammatory acne lesions. Globally, the most intensely researched topical retinoids for the treatment of acne vulgaris are adapalene and tretinoin. A host of topical antibiotics formulations are helpful in inhibiting the growth of commensal bacteria P. acne and reducing inflammation. Most common topic antibiotics available are clarithromycin, azithromycin, and nadifloxacin; however, lack of clinical studies restrain their adoption in various emerging markets.
Global Acne Vulgaris Market: Brief Account
Acne vulgaris is a chronic and most widespread disease of the sebaceous follicles of the human skin. This basically affects the pilosebaceous units which are present in the skin of the chest, back, and face. Many patients…