In this paper, we have introduced some dietary phytochemicals… which could regulate malignant mesothelioma microRNAs.
August 29, 2017
Doctors in Ancona, Italy are calling for more studies on the influence of plant-based phytochemicals on the inner workings of mesothelioma cells. Surviving Mesothelioma has more on the new report. Click here to read the full article.
Researchers at the Polytechnic University of Marche say there is good evidence that many of the phytochemicals that protect fruits and vegetables from threats may also help protect people from the asbestos-based cancer, malignant mesothelioma.
“In this paper, we have introduced some dietary phytochemicals (curcumin, epigallocatechin gallate, quercetin, genistein, pterostilbene, resveratrol, capsaicin, ellagic acid, benzyl isothiocyanate, phenethyl isothiocyanate, sulforaphane, indole-3-carbinol, 3,3′-diindolylmethane, diallyl disulphide, betulinic acid, and oleanolic acid) which have shown microRNA regulatory activities in various cancers and could regulate malignant mesothelioma microRNAs,” writes author Md Abu Sayeed.
According to the researchers, so far, only one phytochemical – ursolic acid found in apple peels – has been shown to regulate microRNA in malignant mesothelioma.
“Given the amount of research on plant compounds released in the last year alone, it is reasonable to imagine that scientists have only scratched the surface of what these compounds could mean for the treatment of malignant mesothelioma and other cancers,” says Alex Strauss, Managing Editor for Surviving Mesothelioma.
For a better understanding of microRNAs and their role in malignant mesothelioma, see Preventing and Treating Mesothelioma with Phytochemicals, now available on the Surviving Mesothelioma website.
Sayeed, MA, et al, “Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma”, August 21, 2017, Biomedicine and Pharmacotherapy, Epub ahead of print, https://www.researchgate.net/publication/318659017_Regulation_of_microRNA_using_promising_dietary_phytochemicals_Possible_preventive_and_treatment_option_of_malignant_mesothelioma
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